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Kaplan Qbank USMLE



Author4 Posts
  #1

chronic long term regulation of enzymatic activity ,as opposed to acute changes in enzymatic activity is best effected by which of the following regulatory controls?

a) covalent modification of enzyme

b)synthesis or degradation of enzyme

c)product inhibition of enzyme

d)availability of substrate to enzyme

e)allosteric control of enzyme


  #2

b)synthesis or degradation of enzyme [think of P450, enzyme inducing agents]

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life is guud

  #3

correctsmiling face and thank u for the hint.

  #4

hello ssrpk, could you let me know the page reference to look this up in kaplan biochem...i am not finding a lot of info. is there a table which gives acute & long term enzyme regulators? I would have thought something like transcriptional regulation (steroid hormones) is chronic while using zymogens, heat, pH or even inducing drugs (which use cytochrome P450) are short term changes... also, is there a good resource to understand covalent modification as a way of influencing enzymatic actions ...i've understood allosteric ('other site' literal meaning) but not clear about covalent modification.. thanks







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