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Kaplan Qbank USMLE



Author2 Posts
  #1

Remember:

Defects of the extrinsic pathway (normal aPTT, prolonged PT) usually indicate early liver disease or coumarin therapy (congenital factor VII deficiency is rare)

Factor VII deficiency
Pittsburgh Pathology Cases

Defects of the intrinsic pathway (normal PT, prolonged aPTT) include factor VIII and IX deficiencies or circulating anticoagulants (congenital factor XI and XII deficiencies are rare)

Defects of both pathways (prolonged PT and aPTT): usually indicate heparin or coumarin therapy, advanced liver disease, or circulating anticoagulants (congenital factor II, V, and X deficiencies are rare)

Defects of neither pathway (normal PT and aPTT): fragile vessels, platelet problem, or factor XIII deficiency (remember urea solubility t

  #2

THANX a lot, i was in so much of need of this material from LONG LONG back n never gt to know it frm any text books clearly.

Gr8 USBuzz !! keep it up


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