reet
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explain plase why ---1 pappiedema 2 seizures 3 hepatitis in vita A toxicity???
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| chemamr
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donīt know, do you have the answer reet??? please tell us 
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| drkpp
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i dont know the pathophys behind it but it leads to a condition called pseudotumour cerebri which has all the listed features. also seen in vit.D toxicity
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| chemamr
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yes, itīs pseudotumor cerebri, i know that but i donīt know the exact physiopathogenic mechanism 
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| ssrpk
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pseudotumor cerebri is also a manifestation of sudden withdrawal of exogenous glucocorticoids.
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| sturge_weber
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well , pseudotumour cerebri is a condition when pts complains of severe headache, more often present retroorbitally, and increases by the movement of eyes, and also causes papilledema, ie swollen optic disc, with hmgs
the cause of this is some problem with reabsorption of csf from the arachnoid villi, and hence increased intracranial pressure, so called coz it resembles features of a tumour.
this is pst in 2 conditions ie vit a toxicty, and sudden withdrawl from corticosteroids{not sure about vit d toxicty} and hence the symptoms
thanks ssrpk, drkpp, chemamr, u guys re great, i wish i were as good as u...
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| drkpp
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sturge well explained.
y wld u want to be as good as me when u seem to be better then me!!!!
keep it comin and study hard
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| ssrpk
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hey sturge , going pretty good man, keep it up!
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| Flying h4x0r
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yeah... just remember to stay away from the polar bear livers
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| drkpp
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thats right. no big game hunting !!!
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| pucha
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Still did not get how EXACTLY (thru what mechanisms) vit A/D causes the villi dysfunction with further impairment of csf reabsorption...Please someone explain!
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| reet
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pucha as sturge weber said----its pseudotumour cerebri== inCreased reabsoption at arachnoid villi---increased CSF...in TOXICITY
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| gpsbrar
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Hummmmm You guys did a good job cracking it down. Good job Sturge and Reet. Well thanks reet for putting this kind of question. I appreciate it my fren.
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