bobby Forum Guru
Topics: 136 Posts: 569
| | 08/20/05 - 08:58 PM  
 
   
 
|   #1 |
A 4-year-old boy presents with severe pains in both of his legs. On physical examination, his temperature is 37.7 C (99.8 F), blood pressure is 108/68 mm Hg, pulse is 96/min, and respirations are 17/min. He is noted to have marked pallor on his lips and palpebral conjunctiva. Numerous purpura and petechiae are noted on his skin. His spleen is palpable 3 cm below his left costal margin. Laboratory evaluation reveals a white blood cell count of 1600/mm3; hemoglobin, 6.1 g/dL; and platelets, 36,000/mm3. Which of the following diagnoses is most consistent with these findings? A. Acute lymphocytic leukemia B. Aplastic anemia C. Henoch-Schönlein purpura D. Immune thrombocytopenic purpura E. Thrombotic thrombocytopenic purpura
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| SDK Forum Fanatic
Topics: 537 Posts: 1,587
| | 08/20/05 - 10:27 PM  
 
   
 
|   #2 |
Acute lymphocytic leukemia or lymphoblastic leukemia???? answer is A...
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| bobby Forum Guru
Topics: 136 Posts: 569
| | 08/20/05 - 11:20 PM  
 
   
 
|   #3 |
can you please explain why the lymphopenia? usually ALL has leukocytosis
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| SDK Forum Fanatic
Topics: 537 Posts: 1,587
| | 08/20/05 - 11:22 PM  
 
   
 
|   #4 |
accumulation of immature cells in the bone marrow supress normal activity of marrow.....this leads to pancytopenia.....as abow picture....
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| SDK Forum Fanatic
Topics: 537 Posts: 1,587
| | 08/20/05 - 11:24 PM  
 
   
 
|   #5 |
pancytopenia also occur in aplastic anemia...but in children ALL is more common..
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| bobby Forum Guru
Topics: 136 Posts: 569
| | 08/20/05 - 11:27 PM  
 
   
 
|   #6 |
so if i get you right, you are trying to say that.... initially there is leukocytosis, which eventually becomes leukopenia. is that what you mean?
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| tamar Forum Senior
Topics: 2 Posts: 105
| | 08/21/05 - 03:53 PM  
 
   
 
|   #7 |
I think the answer is A. Patient has pains in the legs (some pts refuse to walk) also supports the Dx.
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| aliakram Forum Junior
Topics: 2 Posts: 61
| | 08/25/05 - 03:03 AM  
 
   
 
|   #8 |
A..age with hpspmegaly and leg pain usually limping child is seen. Ap Anemia may have some ppt factor and Q Stem lacks any such info.
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| chemamr Moderator and PGY1

Topics: 703 Posts: 4,441
| | 08/25/05 - 03:11 AM  
 
   
 
|   #9 |
in ALL, approx 1/3 of patients have normal leukoc , 1/3 increased and 1/3 decreased.
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