kingsofke
Forum Guru
Topics: 24
Posts: 715
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will cause B block then unopposed action of muscarinic in bronchi will narrrow them down further
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| SDK
Forum Fanatic
Topics: 537
Posts: 1,587
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It is nonselective B blocker....bronchoconstriction.......In COPD pts there is already obstruction.
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| KEROCHI
Forum Guru
Topics: 60
Posts: 971
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you're both right!
Nadolol is a non-selective B-Blocker that will cause bronchoconstriction by blocking theB2 receptors responsible for promoting bronchial smooth muscle relaxation. So if it's given in pts. w/ COPD it will exacerbate the bronchoconstriction that's already present.
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