chemamr
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Which is the diagnostic test of choice for menopause?? i know mainly itīs a clinical diagnosis, but if you have to ask for a diagnostic test, which one would it be?
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| nisha
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you should look for increased levels of FSH (>35IU/L) on day 3 of cycle initially, also look for decreased levels of estradiol. (more imp is lack of menses for 1 year and clinical features of estrogen deficency)
Here's something else important:Absolute contraindications to HRT
A: acute liver disease
B: undiagnosed vaginal bleeding
C: cancer of uterus, breast cancer is considered a relative contraindication
D: DVT (thromboembolic disease)
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| chemamr
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thanks Nisha, thatīs completely correct !!!  
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| d_raza1
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Oral contraceptives should also be contraindicated in ch.liver disease. are they?
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| merrk
Forum Elite
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yup, b/c they are metabolized in the liver.
- Absolute contraindications. Pregnancy, history of thromboembolic disease, stroke or TIA, focal or severe migraine, ischemic heart disease, severe hypertension, history of breast cancer or estrogen-dependent neoplasms, hepatic dysfunction or tumor, porphyria, current prolonged immobilization or recent surgery on legs, diabetes with end-organ damage, smoker (>20 cigarettes/day) over 35. Ask about family history of venous thromboembolism; if positive, consider screening for Factor V Leiden, etc. Relative contraindications. Postpartum less than 3 weeks, lactation, active gallbladder disease, active mononucleosis, undiagnosed abnormal vaginal bleeding, light smoker over 35, long-term use of drugs decreasing the efficacy of the pill (rifampin, rifabutin, griseofulvin, phenytoin, phenobarbital, topiramate, carbamazepine, ampicillin, doxycycline, tetracycline)
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