tdr
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A 35-year-old woman consults an ophthalmologist because of double vision and droopy eyelids. She also has complaints of generalized muscle weakness. IV injection of edrophonium dramatically, but only briefly, reverses her symptoms. This patient's probable disease has a pathophysiologic basis that is closest to that of which of the following conditions?
A. Bullous pemphigoid B. Diabetes mellitus type 1 (some cases) C. Idiopathic Addison disease D. Insulin resistance E. Systemic lupus erythematosus
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| chemamr
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it would be addison?
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| drkpp
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b. sle
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| sethigulshan
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Is it Insulin resistance?
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| sethigulshan
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Why I said was that, because constant stimulation of receptors in both cases leads to receptor desensitization.
I am not sure, I am a Step 1 student. dont mind.
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| tdr
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you are rigth sehigulshan...answer is type 2 DM-insulin resistance
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| chemamr
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  why? could you explain it??
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| drkpp
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the answer is in kaplan step 1 immumonlogy section- hypersensitivity chapter last page table.
it has all the 4 types of hypersensitivites and there examples. i am sure one can find the answer there. just see the column that has myaesthenia gravis. i am not sure since i do not have my step1 books but as far as i recall it is d.m2 and not sle as i stated before.
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