sethigulshan
Forum Senior
Topics: 27
Posts: 146
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Lets start with this!!
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| mildus
Forum Guru
Topics: 19
Posts: 614
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Have you heard for Turet's (maybe Thuret's I'm not sure) syndrom - does it have to do something with basal ganglia?
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| ssrpk
Forum Fanatic
Topics: 154
Posts: 2,819
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Tourette syndrome.
ofcourse it is a/s with basal ganglia lesions involving the indirect pathway tht leads to episodic flare ups of direct pathway (inc. in dopamine) resulting in tics (vocal or motor)
Rx- pimozide
there was an excellent documentary on discorvery once where 30 yr old male pt had tics since his teenage and the anti-dopaminergic drugs were'nt effective anymore; however they performed a surgery and implanted some electrodes tht were activatig his caudate nuclei(indirect pathway) and his tics subsided!
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life is guud
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| mildus
Forum Guru
Topics: 19
Posts: 614
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Thanks ssrpk! I have also watched it on Discovery TV but I haven't understood which part of basal ganglia was involved.
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