I.A.
Forum Newbie
Topics: 3
Posts: 17
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Some useful info
source: Q bank MCQ
Burkitt's lymphoma is actually associated with three translocations. The common variant t(8;14)(q24;q32), involving the oncogene myc on chromosome 8, and the heavy immunoglobulin chain on chromosome 14. The other two variants are: t(8;22)(q24;q11), involving myc and the lambda light chain immunoglobulin site, and t(2;8)(p12;q24), involving the kappa light chain and myc.>Mantle cell lymphoma, multiple myeloma, and small (not cleaved) cell lymphoma are associated with the t(11;14)(q13;q32) translocation involving bcl -1 and the heavy chain site.Small cleaved cell lymphoma is associated with t(14;18)(q 32;q21), involving the immunoglobulin chain site and bcl-2.
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| Flying h4x0r
Forum Junior
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Posts: 51
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Thanks!
these translocations are very HY...
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| p53
Forum Guru
Topics: 51
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Terms 'Small cleaved cell lymphoma, Small noncleaved cell lymphoma' are from outdated classification, named 'working formulation'. In the new 'WHO classification of lymphoid neoplasms' (modified REAL classification) we don't have these names and we shouldn't use them any more.
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| ssrpk
Forum Fanatic
Topics: 154
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they may be outdated but i think i recall one of these terms on my exam, better know couple oif these!
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