Prep for USMLEPrep for USMLE
         Forum      |     Resources New Posts   |   Register   |   Login





 CSF in Guillain-Barre syn.  
Get Adobe Flash player



Post Reply  
  • 0/5
  • 1
  • 2
  • 3
  • 4
  • 5


Author10 Posts
  #1

CSF findings in Guillain-Barre syndrome?

1.High cell / low protein

2. High cell / high protein

3. Normal cell / high protein

4. Normal cell / low protein



  #2

after 7 days of onset of illness, LP shows high protein and normal Cell counts/acellularity

its called albuminocytologic dissociation - because normally in meningitis and all, the cell count rises along with the rise in proteins but in the case of GBS, it doesn't happen.

so choice 3 is the answer



  #3

3 (high proteins and normal to mild elevation of cells with lymphocytes)

smiling face



  #4

drvic wrote:
after 7 days of onset of illness, LP shows high protein and normal Cell counts/acellularity

its called albuminocytologic dissociation - because normally in meningitis and all, the cell count rises along with the rise in proteins but in the case of GBS, it doesn't happen.

so choice 3 is the answer



good explanation drvic



  #5

Indeed!



  #6

but why?


  #7

Yeah, 3
why?
Guillain Barré is not an infectious disease(unlike meningitis). This is why cells r not elevated. Though precipitated by recent infection, it is however an autoimmune reaction, leading to distruction of schwann cells with demyelination of peripheral nerves.
I do in fact wonder why the protein is elevatedraised eyebrow
One of the proteins found in CSF in GB is haptoglobin


  #8

This is a pretty "classic" question, isn't it? CSF findings in GBS... there's a specific term for this, isn't there? That... "albuminocytologic dissociation" that professors always banter on about. So I'm pretty sure the answer is 3 (normal cells, high protein).


  #9

@raymd. coz i think myelin is protein...thats why its raised


  #10

The reason why protein is elevated is because of increased IMMUNOGLOBULINS. Remember they are proteins too!





Bookmark and Share



This thread is closed, so you cannot post a reply.



Login or Register to post messages








show Similar forum topics

Guillain Barre Syndrome
Guillain Barre Syndrome
guillan barre synd
show Related resources









Advertise | Support | Privacy | TOS | Premium | Contact