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Kaplan Qbank USMLE



Author6 Posts
  #1

intravenous administration of a substance results in decreased mean arterial blood pressure.lab studies show that the substance is inactivated by peptidases.the substance is

angiotensin II

bradykinin

histamine

neuropeptide Y

serotonin


  #2

histamine

  #3

its bradykinin.......

  #4

histamine is very short lived...about 6 min and causes dilation by endothelial cell contraction...Brady o the other hand is about 30 min and cases separation of tigh junctions and free passage of vascular fluid in to interstititum.

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  #5

correct answer?

  #6

bradykinin is correct, key point to identify is inactivation by peptidases [ACE]

histamine undergoes inactivation by MAO and DAO!


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