SDK
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How IgA pass thru epithelial cells not other Igs????
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| p53
Forum Guru
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Dimeric IgA with J chain binds to the poly-Ig receptor on the basolateral surface of epithelial cell and is transcytosed to the apical surface. Here poly-Ig receptor is cleaved, fragment of it under the name of secretory component releases bound with IgA and protects it from proteolytic cleavage.
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| SDK
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Nice explanation......
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