chemamr
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Which are the differences between Myasthenia Gravis and Lambert Eaton Syndrome?
- Main defect
- Signs and symptoms
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| ns11266
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myasthenia gravis:autoimmune destruction of post synaptic ach receptor.
eaton lambert:non metastatic manifestation of small cell carcinoma of lung.Threr is defective ach release at NMJ
both present with proximal muscle weakness,ocular muscle weakness
in myasthenia,reflexes are initially preserved
In EL reflexes are absent.
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| ayeshah_l
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in Eaton Lambert the pahtology is in the presynaptic Ca+ channels
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| mani
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in myesthenia the strength of contraction decreases with continued activity and it increases with continued activity in eaton lambert syndrome
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| chemamr
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Correct, I could add:
-Eaton Lambert: P/Q type Ca+ channels are defective. There are less oculbar/bulbar symptoms than in MG.
You´re right. 
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