Congestive Heart failure

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Congestive Heart failure

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doc2003
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05/03/05 - 02:44 PM

Experimental drug was given to someone with severe congestive heart failure. Within minutes of IV administration there is a decrease in cardiac afterload and preload. Also an increase in GFR. The effects of the drug are most similar to those produced by which of the following?

1- aldosterone
2- insulin
3- Angiotensin 2
4- norepinephrine
5- ADH
6- ANP

ssrpk
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05/03/05 - 03:24 PM

6- ANP

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doc2003
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05/03/05 - 03:46 PM

thanks for the response ssrpk...but why did you pick anp I thought it was angiotensin 2.....I dont have an ans for this question.

ssrpk
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05/03/05 - 04:25 PM

insulin has no significant activity on vessel contractility

others listed increase either preoload or afterload execpt ANF!

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gooshipoh
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05/11/05 - 01:45 AM

angiotensin 2 constricts peripheral bld vessels, increasing TPR afterload and it causes aldosterone synthesis increasing preload.

SDK
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05/11/05 - 04:24 AM

How ANP inc: GFR???

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anjushree
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05/26/05 - 08:37 AM

ANP causes vasodilatation of peripheral resistance vessels

ssrpk
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05/26/05 - 01:04 PM

ANP antagonize the effcts of ADH and angiotrensinII

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gooshipoh
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05/26/05 - 04:18 PM

well i think ANP incr GFR b/c it decr BP and that slows down blood allowing more to filter.

ssrpk
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05/27/05 - 01:20 AM

#10

u are rite gooshipoh!

ANP does inc. GFR by constricting efferent and dilating afferent; also reduces Na+ and H2O reabsorption in the CD

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