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Kaplan Qbank USMLE



Author2 Posts
  #1

I cannot solve this problem.


Two lab mouse strains (A and B) differ in their DNA at 2 unlinked loci (strain A has allele A at locus 1 and allele A’ at locus 2; strain B has allele B at locus 1 and allele B’ at locus 2; no apparent phenotypic difference is visible).

a. If strains A and B are crossed to give F1 hybrids, and 1 male and 1 female from the F1 are chosen to mate, what fraction of their progeny (the F2) will be heterozygous for both genes?

b. If 1 male and 1 female are chosen from the F2 to mate, what is the chance all their progeny will be homozygous at both genes?

c. How many mating pairs from the F2 (1 male and 1 female chosen at random) should you establish to expect 1 pair to give all progeny with BB at locus 1 and A’A’ at locus 2?

  #2

i feel something missing in q.
did any one got the ans?







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