bluestar
Forum Guru
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please ?
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| amitjosh
Forum Senior
Topics: 9
Posts: 116
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I havent read it in a long time, but as far as I think,
ACE inhibitors should not cause renal artery stenosis.
However, if the person already has bilateral renal artery stenosis, and basically that sort of leads to a prerenal failure, the only compensatory mechanism left for the kidney then, is the renin-angiotensin-aldosterone axis, to increase the renal blood flow, gfr, etc.
If you are blocking the renin angiotensin aldosterone mechanism in a patient with bilateral renal artery stenosis, you will precipitate a renal failure.
However, I have not read anywhere that ACE inhibitors cause renal artery stenosis.
Hope that makes sense,
Amit Joshi.
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| dacis
Forum Junior
Topics: 1
Posts: 75
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You are right - ACEI don't cause renal artery stenosis , but they do lead to renal failure in Pt. with renal artery stenosis .
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| bluestar
Forum Guru
Topics: 236
Posts: 724
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That's very clear. Thank you guys a lot!
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| bluestar
Forum Guru
Topics: 236
Posts: 724
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one more question, since ACEI is contraindiated in bilateral renal artery stenosis, why do we still use captopril renogram as the initial screening test for renal artery stenosis? I am confused...
:roll:
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