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  #1

And their action mec. ?????

  #2

antiemetics as the name indicates are to supress vomiting for eg. pt undergoing chmotherapy!

remember it this way:

CENTRAL EMESIS CENTRE [reticular formation of the brain stem]

receives input from following sources:

a- CTZ [monitors blood and CSF]
b- Vagus NTS - Splanchnic afferents [gut]
c- Cerebral cortex [anticipatory]
d- Vestibular apparatus [motion sickness]

Drugs MAO's are:

-5HT3 antagonists [ondansetron]
-D2 antagnists [metoclopramide/promethazine]
-H1 antagonists [cyclizine]
-M antagonists [scopolamine-famous transdermal patch for motion sickness]
-cannabinoid agonists [dronabinol]
-corticosteroids are also supplemented in particular to control CTZ induced!

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