mjl1717
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1)tyrosinase uses copper
It converts tyrosine to dopa (to eventually form melanin)
2)Also lysyl hydroxylase uses copper to form the cross links between the aldehydes of lysine
3)dopamine B hydroxylase uses copper and vitamin C in catecholamine synthesis(NE)
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| amg
Forum Newbie
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Lysyl oxidase requires copper (not lysine hydroxylase) as cofactor to form cross links def of which causes Menkes disease.
Lysine hydroxylase & proline hydroxylase req Vit c def of which cause scurvy
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| ssrpk
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cytochrome oxidase is a Cu++ containing heme!
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| anjushree
Forum Guru
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cu is a cofactor for
1)FERROXIDASE-bind Fe to transferrin -in def lead to anaemia
2)Lysyl oxidase-for crosslinking of collagen- in def leads to abnormal collagen,Arterial tourtuosity &rupture &osteoporosis
3)cytochrome oxidase-a com of ETC-IN DEF lead to cerebral degenertion(brain req ATP)
4)tyrosinase-enz for melanin sys-in def lead to depigmentation
5)also in superoxide dismutase
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| mildus
Forum Guru
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good
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