 |  ANTIPSYCHOTIC NOTES......
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| Author | 1 Posts |
GUEST
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Anti psy drugs…mech of action..
Typ
More potency more extra pyr effects less sed
Block dop receptors at BG soo more extra pyr effect
ATYp
Less potency less extra pyr more sed
Risp acts on D2
Clozapine D 4
SIDE EFFECTS
ANTI CHOL…..dry mouth confusion urin retention
constipation delirium blur vision
CARDIAC…..risperidone increases QT interval sooo card ARRY
HYPOTENTION…..rispe….due 2 alpha receptor blocked
Mostly due 2 low potency drugs
SEDATION……due to anti his effect
AGRAN….d/t clozapine
ENDO…..resp….gynaecomastia..ammen….galactoria
DERMAL & OCULAR…..esp thioridazine…pig retinopathy….
REDUCED SEIZURE THREAHOLd….esp clozapine…
WEIGHT GAIN…..olazapine
MOVEMENT DISORDERS acute
PARK(bradykinesia)
Slow movement increase mle tone resting tremors….
Mostly in elderly
Treat with
Anti chol like tri hexyphenidly or benztropin
ACUTE DYSTONIA
Spasm of musle groups like oculogyric….buccolingual ..opthithotonus…..
Mostly in young….
Treat by
Anti chol like benztropin ..I/V opr I/M
AKATHASIA
Restlessness…treat with
Propranalol…
TARD DYSKINASIA
Choreoathetosis…invol mm…first of tongue & fingers then trunk
Switch 2 clozapin….
MALIG NEUROLEPTIC SYN
Mle rigitidy & increased temp..
Giv dantrolene & bromo
SOME IMP SIDE EFFECT
Thioridazine….photo sen & pig retinopathy & retrogardae ejac…
& galac..ammen
Clozapine…..agran …seizure….sed….wt gain..sialoorrhea…
Risp….less sed less extra ..less anti chol
Quetrapine…cataract
TREATMENTS….
For psycho motor agi & delusion…………….HALO 5mg I/M hourly some add lorazepam
For SCHIZO…. Resp
Delirium……..HALO
Dementia…..resp
ALZ………..resp.
HUNTINGtonz…....HALOPER....
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