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Methionine, as the universal start codon, begins all mRNA sequences, however, it is sometimes removed as part of a post-translational modification.
Question: What percentage of mature proteins have methionine at their N-terminus? I would appreciate an estimate from peer-reviewed literature, or, if you have a lot of experience in post-translational modification, a ballpark-type estimate would be great.
Any help would be much appreciated!
Bret
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