doc4life
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How r these 3 ( isotype , alotype , idiotype ) different ?
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| mjl1717
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Isotype -The class of an antibody heavy or light chain, IgM ,IgE IgA are examplesof different isotypes
Allotype -The genetically determined difference in a molecule between members of the same species.( ususally result from substitution of only one or two amino acids in the constant region usually of heavy or light chains)- No biological significance
Idiotype-The individual ,unique differences between antibodies of different antigen-binding specificities. Idiotypes are determined by the structure of the variable regioons of antibodies.
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