ssrpk
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which of the following components of the second messenger cascade is directly responsible for the release of intracellular store of Ca+?
(A) cAMP
(B) Diacylglycerol
(C) G-protein
(D) Inositol 1,4,5 triphosphate
(E) Nitric oxide
(F)protein kinase
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| att
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B) Diacylglycerol
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| mjl1717
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my reflex response would have been answer-d(inositol)
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| ssrpk
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i am aslo confuse b/w b & d
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| kmp
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Ans (D) Inositol 1,4,5 triphosphate
Agree with mjl 1717. IP3 induces release of Ca from sarcoplasmic reticulum. This Ca along with DAG activates protien kinase C.
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| mjl1717
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Isn't this associated with a major receptor??
Anyone know , I forgot.
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| ssrpk
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Gq causing IC inc. IP3 and DAG a/s with alpha 1 , muscarinic 1.......!!!!
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| alessandra SR
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It is IP3 who stimulates Ca release from endoplasmic reticulum. The calcium released will help in the reaction from Diaglycerol to increase protein kinase C
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