mjl1717
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Whats the most common method of cancer cells becoming resistant to methotrexate?
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| ssrpk
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MDRP ???
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| mjl1717
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Incorrect
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| kmp
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Resistance in cancer cells can be due to amplification(production of additional copies) of genes that codes for dihydrofolate reductase resulting in increased levels of this enzyme.
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| mjl1717
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Yes, the key word- amplification.
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