phuluong2k
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An african woman go to your office with diagnosis of sarcoidosis. You need to prescribe an diuretic, Which one is most appropriate ?
A. Thiazide
B. Acetazolamide
C. Manitol
D. Furosemide
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| ssrpk
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i don't get the clue from sarcoidosis.....so ill go with the first line of agent
A-thiazide
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| kmp
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I will go with D ) Furosemide.
in sarcoidosis there will be hypercalcimia and thiazides increase calcium levels .
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| mjl1717
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Of course, kmp has it right and is giving good information "Lovely Lasix"!
keys:
1)ACE levels
2)hilar adenopathy
3)E. nodosum in a relatively young black female
4)noncaseating granuloma
Also Acetozolamide would tend to put her toward metabolic acidosis
Mannitol effectively dilutes intraluminal sodium conc. and markedly
INCREASES tubular flow rate. Extra-*mannitol and urea are osmotic agents
known for being 2 of the most rapid and freely filtered agents at the glomeruls!
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| phuluong2k
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Yeah, you are right
And sarcoid macrophage secrete 1,25 Vit D :arrow: Hypercalcemia
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