krishie
Forum Senior
Topics: 17
Posts: 128
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Hi,
In case of diseases like fragile X ,there will be a trinucleotide expansion of untranslated region.Since the mutation occurs in untranslated region,how can it actually cause a disease?Untranslated areas do not proceed to become a part of MRNA,rt?Could someone explain please,?Thanx!
Krishie
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krish
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| focussed
Forum Newbie
Topics: 2
Posts: 33
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untranslated regions are a part of mrna,because they do are transcribed.they are the sites where ribosomes will first bind to start the protien synthesis at 5 ' end and also help in termination at 3' end.so if these sequences are mutated protein synthesis will be affected.
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focussed
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