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Kaplan Qbank USMLE



Author6 Posts
  #1

This thread may be used to post personal review notes for Physiology.
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HEMOSTASIS
A)Def:
Sequence of events leading to cessation of bleeding by formation of stable platelet hemostatic plug..........
B)Include:
1)Vascular wall:

--->Transient vasoconstriction by endothelin.
--->Release tissue factor activate VII(extrinsic)
--->Expose subendothelial collagen activate XII(intrinsic)
--->Release vWF
--->dec: synthesis of antithrombic---PGI2,NO,tPA,thrombomodulin.
2)Platelet plug formation:
--->platelet adehesion. with vWF thru GP-Ib
--->platelet activation. degranulation & exposure of PL complex
--->platelet aggregation. by platelets with fibrinogen thru GP-IIb & IIIa....
vicious circle---plug forms.
3)Coagulation pathways:

___________________
Love humans,save humans & live like humans.

  #2

Pollack GH, 2001. Cells, Gels and the Engines of Life: A New, Unifying Approach to Cell Function. Seattle, WA, Ebner & Sons.

Pollack's recently published book (Pollack, 2001) cannot be correctly understood if it is taken out of the context from the scientific ideas first introduced by Gilbert Ling in his Association-Induction Hypothesis (AI hypothesis: Ling, 1962, 1984, 1992, 2001) and other closely-related writings (Nasonov, 1962; Ernst, 1963; Troshin, 1966), because not only does it deal largely with AI hypothesis, but it is presented as a relatively random collection of fragments. Both the uniqueness of the AI hypothesis as the first unifying physicochemical theory of life, and the fact that it has stood 40 years of world-wide criticism are not even briefly mentioned. As a result, one could easily be misled into believing that it is Pollack rather than Ling who had introduced this unifying theory of cell function. The possibility of doing harm by an unbalanced presentation of the material is going to be greatly exacerbated by the lack of familiarity of most biologists with the AI hypothesis.

To be continued here: http://www.bioparadigma.spb.ru/reviewonpollack.ht...

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  #3

How do I get your complete notes for the section I am replying to. Thank you for doing it. E-mail:ISelassie@aol.com.

Thanks!

  #4

I am discussing here an equation of acid base balance.....
H+=PCO2/HCO3.
H+ is directly proportional to PCO2 & invers: to HCO3...
This mean that,
1)If We raise H+ conc: then it will inc: PCO2 & dec: HCO3
2)If we raise PCO2 then it will raise both H+ & HCO3
3)If we raise HCO3 then it will raise PCO2 but dec: H+.
& vise versa occur....
Now in point no:2 there is another compensation occur which dec: H+ is inc: secretion of H+ with inc: reabsorption of HCO3 & hyperventilation..

___________________
Love humans,save humans & live like humans.

  #5

wrote:
I am discussing here an equation of acid base balance.....
H+=PCO2/HCO3.
H+ is directly proportional to PCO2 & invers: to HCO3...
This mean that,
1)If We raise H+ conc: then it will inc: PCO2 & dec: HCO3
2)If we raise PCO2 then it will raise both H+ & HCO3
3)If we raise HCO3 then it will raise PCO2 but dec: H+.
& vise versa occur....
Now in point no:2 there is another compensation occur which dec: H+ is inc: secretion of H+ with inc: reabsorption of HCO3 & hyperventilation..

Absolutely wrong equation and wrong approach

GL


  #6

ACID BASE BALANCE EQUATION SOME OF IT TRUE SOME ARE VERYWRONG EVEN MATHEMATICALLY SPEAKING







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