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Kaplan Qbank USMLE



Author6 Posts
  #1

Synthesis of which of the following occurs predominently during the S phase?

a.cyclins
b.DNAses
c.histones
d.RNA polymerases
e. snRNPs
f. tubulins


Plz give explanation

  #2

Ans C histones.
DNA replication takes place during the S phase.

  #3

What about
F. Tubulins, in preparation for mitosis?

  #4

Tubulins will be in G2 phase.

  #5

This how I do it:

Interphase is: G1--S --G2/ Division occurs in Mitosis-M-phase.

G1 is the Gap between birth and DNA synthesis! (At the end of G1 centrioles pair)
G1-RNA, protein, carbs and lipod synthesis also occurs about 5 hrs.
S-chromosomal protein(eg.histones) synthesis occurs about 7 hrs.
S---*Histones are synthesized and combine with DNA/centrioles complete there replication during S phase
G2 a gap before mitosis ATP synthesis occurs about 3 hrs.
M-Mitosis

check point -At G1 is 2 cyclin D&E
check point -At G2 is 1 cyclin A&B
p53 anti oncogene can shut off cell cycle
cyclins are degraded during anaphase of the M phase.

So my answer is C.
good q!

___________________
Smell the coffee! "Is That an Osler move??"

  #6

OK, thanks







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