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Author3 Posts
  #1

Anyone know what megaloblastic madness is? What are the symptoms and typical presentation?

  #2

Neurologic symptoms related to vitamin B12 deficiency occur most commonly in the fourth through sixth decades. Confusion, memory loss, paranoia, hallucinations, depression, and irritability are all features of the neuropsychiatric syndrome that has been described as megaloblastic madness.

Importantly, among those with cognitive and behavioural symptoms and vitamin B12 deficiency, as many as one fourth do not have the megaloblastic anaemia that is classically associated with pernicious anemia.

  #3

Thanks Phuluong. Just what I needed!







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