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Kaplan Qbank USMLE



Author11 Posts
  #1

A 32-year-old female who is 6 months pregnant presents for prenatal
care. A routine evaluation is performed, including testing for HIV
antibody. The patient is reported to be negative for RPR, but positive
for HIV antibody by the enzyme-linked immunoassay (EIA). The HIV Western
blot is positive for antibody to the p24 antigen. The patient should
be counseled
A. that she and her baby were both infected with HIV
B. that she had a false-positive HIV EIA
C. that she is negative for HIV since the RPR was negative
D. that she is positive for the HIV virus
E. to have an HIV polymerase chain reaction (PCR) test performed

  #2

E. to have an HIV polymerase chain reaction (PCR) test performed?

  #3

can u please explain it to me?

  #4

this q also posted before also on this forum.
and i chose the answer a.
but i don't have explanation dear.
may be sone one else explain us.

  #5

thank you anatomy....

  #6

ok, i was confused between D and E. PCR is done to determine the viral load to assess treatment, but the thing is that in pregnant women u don't need the viral load to start treatment, u just need confirmation for hiv being +ve, which in this case we have, so i think that we are left with D.

i hope this solved your problem.

  #7

This is the way in diagnosis of HIV

First ELISA look for p24

If negative :arrow: Have not HIV infection
If positive :arrow: Take Western blot


Seconly Western blot: look for manay other antigens, but the 3 important antigens are p24, gp41, gp 120.

:arrow: Test negative: have no any antigen :arrow: Have not HIV

:arrow: Test positive: have at least 2 antigens positive :arrow: HIV confirmation

:arrow: Test intermediate: have only 1 antigen positive (in this case)


In the case of intermediate test :arrow: Take another western blot 6 months later or take PCR test immediately


Hope this help

  #8

hey phuluong
thanks for providing such imporatant information in such an easy manner.

the answer given is E)

  #9

agree with phuluong2k....nice explanation.
The ans is E

  #10

phuluong2k thanx for nice information.

  #11

i would take d

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