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Kaplan Qbank USMLE



Author3 Posts
  #1

10 y o child, has symptoms ressembling Hurler syndrome, with gargoyle facies, cardiac, CNS, skeletal abnormalities. Biochemistry defect is inability to add the marker mannophosphate to enzyme. In which of the following does this step usually occurs

A. ER
B. Golgi
C. Lysosome
D. Mitochondria
E. Ribosome

  #2

answer-golgi

Accumulation of mannose is in E.R., phosphorylation usually in golgi, but degradation is in lysosome.
Good q.

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  #3

GOOD ANSWER smiling face







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