rubensssss
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-the SNS refers to the division of the ANS arising from the theracic and lumbar regions of the spinal cord.
a. ACh is the neurotransmitter in the ganglionic synapse; and NE is the neurotransmitter at the neuroeffector synapse. Exceptions include:
THIS IS MY QUESTION. Where am I?
1-N-Cholinergic innervation of some adrenal medula.
This mean that N-Cholinergic is a receptor in adrenal medula or is acting as neuro transmitter?
2 Sympathetic M-Cholinergic innervation of the sweat glands.
3-Sympathetic M-Cholinergic innervation of some muscle blood vessels
4- Sympathetic dopaminergic innervation of renal blood vessels.
What are they tolking is about them been a neurotransmitters or cholinoceptors? can anyone explain it to me, the more easy that you can.
Thanks.
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| ssrpk
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all thr pre-ganglionic nerves synapsing with the cell bodies of post-ganglionic nerves has acetylcholine as neurotransmitter(regardless of sympathetic or parasympathetic)
1- adrenal medulla...they are modiefied postganglionic neurons and receive their pre-ganglionic innervation via splanchnic nerve....so NT is acetylcholine...
2- sweat glands - they are exceptional in tht they hv post-ganglionic sympathetic innervation and still acetylcholine act their as a NT.
3-muscle blood vessels - there are soe cholinergic innervation to some muscle vascular bed which may contribute to inc. in blood flow during excercise but tht is not all significant practically.
4-renal vessels - post ganglionic symapthetic limb to renal vasculature has some dopaminergic innervation tht results in natriuresis
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| rubensssss
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ssrpk
Thanks, very good explanation.This is wath
I understood
In the SNS NE will act as NT, exept in the place mentioned:
Adrenal Medulla
Swet gland
Muscle blood vessel
Renal blood vessel
N-cholinergic will be the receptor and ACh will be the NT, not NE.
M-Cholinergic also will be the receptor for ACh which acts as NT.
Dopaminergic will be a receptor and ACh the NT.
N-cholionergic = nicotinic receptor
M-cholinergic = muscarinic receptor
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Ruben sssss
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| ssrpk
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look adrenal medulla is no exception.....consider it a sympathetic organ with secretes catecholamine...it receives pre-ganglionic innervation which has acetylcholine just like everywhere else in the body....
nicotinic receptors are present at neuromuscular junctionnot a part of SANS
where there is dopaminergic innevation by SANS (renal vessels) definitily dopamine receptors are gonna be present....
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