ssrpk
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well reduced surfactant due to decrease production os steroids in fetus...
and gestational diabetes will deliver excess glucose to fetus :arrow: inc. in fetal insulin secretion......
whtz is tht link b/w these twoi states?
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| phuluong2k
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Insulin has anti-surfactant formation effect
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| ssrpk
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thnx- did'nt know it
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| knasim
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Insulin inhibits the accumulation of mRNA for the surfactant-associated proteins A and B (SP-A and SP-B) in human fetal lung. In other words gene expression for SP-A and SP-B is inhibited.
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| ssrpk
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tht's kool...thnx knasim
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