Anno Domini
Moderator
Topics: 293
Posts: 727
|
Can somebody explain thr significance of laplace law for blood vesels.I am not sure if i understand that.
|
| mjl1717
Forum Hero
Topics: 958
Posts: 5,465
|
Remember that small aveoli have higher collapsing pressure and ar e harder to keep open compared to large alveoli with a low collapsing pressure and are easy to keep open. Surfactant decreases surface tension
,prevents esp. small alveoli from collapsing and increases compliance(compliance means in general to make it more like a ballon).
Laplace Law puts it in mathematical terms that the pressure tending to collapse alveoli is directly proportional tosurface tension and inversely proportional to alveolar radius.
P=2T/r P is pressure required to keep alveolus open
T is surface tension
r is radius of alveolus
Most of the formulas for vessels are variants of Ohms ubiquitious law and universal law Flow equals pressure over resistance.
Also in vessels wall tension is the force in the vessel to split the wall open.
Laplace claims T is proportionalo to P times r
T=wall tension
P=pressure
r=radius
I hope this helps
___________________
Smell the coffee! "Is That an Osler move??"
|
| Anno Domini
Moderator
Topics: 293
Posts: 727
|
 Thanks
|
| Lorena
Forum Elite
Topics: 9
Posts: 237
|
hope this helps and makes it clearer.
Law of Laplace states that transluminal pressure varies inversely with vessel radius and is directly proportional to tension that develops in the vessel walls. it means the pressure pushes against the wall causing them to stretch= tension, as the size of the vessels decreases the tension in the wall decreases too.
Have a nice studying day!
|
| oddissy4u
Forum Guru
Topics: 107
Posts: 389
|
T=Pr.
T proportional to r , eg in aneurysm =more likely to burst becos of increased r even more thn aorta with more P.
hope this help .....
|
|
| |
| | | | | |
