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Kaplan Qbank USMLE



Author5 Posts
  #1

1 Main C21 hormones (3)
2 Main C19 hormone
3 main C18 hormone
4 z. glomerulosa lacks this enzyme
5 Leydig cell lacks this enzyme
6 main hormone produced in z. reticularis
7 can granulosa cell produce progesterone
8 theca interna cells 3 end products
9 What 2 enzymes compete for 17-OH progesterone in z. fasciculata and reticularis and which one dominates in these cases
10 name the most potent androgen
11 write down the two ways of producing estradiol from andostrendion in the granulosa cells
12 regarding to theca interna are 17-OH, Aromatase, 21-OH or 17-HSDH expressed---what about the granulosa cells
13 which type of estrogen is synthetised comlpetely from fetal substrates-what is its clinical use
14 the enzymatic pool of the trophoblast cells is similar to which maternal cells
15 main 3 steroid hormone products of placenta
16 what happens with DHEAS in the fetal liver

  #2

1) Progesteone, cortisol, aldosterone
2)DHEA, Androstenedione, testosterone
3)estrone estradiol
*Ill return- must go to library!

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  #3

4 z. glomerulosa lacks this enzyme ---17 alpha hydroxylase

5 Leydig cell lacks this enzyme ----21 beta and 11 beta hydroxylase

6 main hormone produced in z. reticularis -------Androgens

  #4

7 Yes, they can

8 Theca cells produce testosterone and estrogen

  #5

9 - 21 -beta hydroxylase and 17,20 lyase compete for 17 alpha progesterone however the dominant one is 21- beta hydroxylase because the major output is cortisol.

10 - dihydrotestosterone

11- androstenedione is converted to testosterone by 17 alpha HSD and the into estradiol by way of aromatase.

12 - aromatase activity is mainly carried out by granulosa cells.....and the major output through the theca cells is testosterone however little if all enters the general circulation and all of them are converted to estradiol.

13 - estriol - useful good index of fetal well being

14 - ......? somatotropes??

15 - progesterone, placental lactogen and estriol

16 - modified by hydroxylation

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