dr_singh246
internal medicine pgy2
Topics: 235
Posts: 561
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A 26-year-old white female presents to the outpatient clinic complaining of an expanding rash. Her social history is significant for recent backpacking along the Appalachian Trail in New England. The rash is localized to her upper back, and it appears erythematous and circular with central clearing. The patient recalls no tick bite. Doxycycline is initiated. What is the make-up of the vaccine recommended in endemic areas?
A. Bacillus Calmette-Guerin (BCG)
B. Live, attenuated bacterium (acid-fast negative)
C. Outer-surface protein
D. Polysaccharide conjugated to toxoid
E. Toxoid
F. Vi capsular polysaccharide.
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| almina
Forum Senior
Topics: 34
Posts: 99
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answer - C.
Vaccine contains a genetically engineered protein from an outer surface protein of B. burgdorferi. The surface protein, called OspA, stimulates antibodies that appear to disable the bacterium's ability to infect the individual
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