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Author2 Posts
  #1

Ten months after starting procainamide for cardiac arrhythmias, a 56 year old man develops arthritis and other symptoms consitent with drug induced SLE, result of a blood test are positive for antinuclear Ab, this finding is consistent with which of the following genetic polymorphsim in drug metabolism ? Explain.

A. Debrisoquine 4 hydroxylase deficiency

B. Erythrocyte catechol O methyltransferase deficiency

C. Glucose 6 phosphate dehydrogenase deficiency

D. Phenytoin hydroxylase deficiency

E. Slow acetylator phenotype

  #2

answer -e

good q!

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