anatomy
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A 45-year-old woman is hospitalized after an automobile accident. The physician collects
1.44 L of urine from the patient in a 24-hour period. The clinical lab returns the following
results:
Plasma creatinine concentration 2.0 mg/mL
Plasma urea concentration 15 μmol/mL
Urine creatinine concentration 100 mg/mL
Urine urea concentration 160 μmol/mL
What is the approximate glomerular filtration rate (GFR; in mL/min) of this patient?
A. 10
B. 25
C. 50
D. 75
E. 100
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| RuMi
Forum Newbie
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D. 75
Use creatinine concentrations : CL = (Uc x V) / Pc = (100 x 1.44)/2
I hope I did that right. :?
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| Alina T
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u want it in ml/min
(100/2) x(1.44x1000/1440)=50
so ans is C
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| mjl1717
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Lots of room for error!!!
Most inportant-try to do in 1 minute:
1)we know uv/p using creatinine
2)change 1.44 L/24hrs to--- 1440ml/24hrs
3)eventually the numerator is 144000mg/ml/24hrs
4)denominator-2mg/ml
5)=72000mg/ml/24hrs
6)24 hrs =1440 minutes
7)**72000mg/ml/24hrs/1440minutes=50mg/ml/ min
8)We could cancel out mgs. get= 50 ml/min
Any COMMENTS on how to do this quicker!!
Good q antomy!
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| kmp
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agree with mjl1717
lots of room for error
i would go with u/p X v (try to keep the same units )
u/p has the same units mg/ml (100/2)=50
and v has 1.44 liters for 24 hours (so convert it to ml/min 1.44X1000 /60X24)
1440/1440 =1ml/min
so u/p X v = 50 X 1ml/min = 50ml/min ( ans C)
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| RuMi
Forum Newbie
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kmp....right on ! i think thats the best way. just cancel the units on u/p, then figure out the units for V according to what the question asks for. Thanks. :!:
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| anatomy
Forum Guru
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Posts: 423
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thanx kmp i think this is the best way to calculate.
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