mjl1717
Forum Hero
Topics: 959
Posts: 5,467
|
This enzyme 5 alpha reductase is responsible for which body parts?
___________________
Smell the coffee! "Is That an Osler move??"
|
| Alina T
Forum Elite
Topics: 17
Posts: 388
|
epididmys, ductus deferens, seminal vesicles, prostate
___________________
There are 3 types of people: those who make things happen, those who watch things happen, and those who wonder what happened.
|
| mjl1717
Forum Hero
Topics: 959
Posts: 5,467
|
prostate is correct but the othere arent.
There is more!
___________________
Smell the coffee! "Is That an Osler move??"
|
| usmleasr
Forum Guru
Topics: 105
Posts: 970
|
5-HT is responsible for development of prostate and external genitalia
|
| mjl1717
Forum Hero
Topics: 959
Posts: 5,467
|
I always thought 5 HT was a precursor to serotonin.(before it was decarboxylated) :roll:
___________________
Smell the coffee! "Is That an Osler move??"
|
| Alina T
Forum Elite
Topics: 17
Posts: 388
|
OOPS!!!
i rushed with an answer to a q that i thought too simple and look!
DHT is responsable for developing of prostate, penis, scrotum
TESTOSTERONE is responsable for developing of epididimys, ductus deferens, seminal vesicles, ejaculatory duct.
mjl thanks for bringing this basic issue up!
now if we came to this, can someone explain why in 17alphaHSD deficiency the parts developing under Testosterone influence are NORMAL? shouldnt they be underdeveloped because of lack of the enzyme that converts androstenedione to testosterone??
___________________
There are 3 types of people: those who make things happen, those who watch things happen, and those who wonder what happened.
|
| usmleasr
Forum Guru
Topics: 105
Posts: 970
|
"usmleasr" wrote:
5-HT is responsible for development of prostate and external genitalia
sorry ...I made a blunder...I wanted to say DHT ..but said 5HT...slip of tongue...typing :oops: ...5HT is 5 hydroxy tryptamine...I am sorry to confuse u mjl
|
| mjl1717
Forum Hero
Topics: 959
Posts: 5,467
|
No I wasnt confused.
But thats something else a q might seem too easy. And it could be easy to miss something that you "KNOW"
Ill be the first to admit Im not good enough to "win" and miss something that I know.(Some can do that!)
5HT :arrow: serotionin, testosterone-5 alpha reductase dihydrotestosterone
The 5 HT Im talking about is 5 Hydroxytryptophan, the immediate precursor to serotonin. What your talking about is an alternate name for serotonin
___________________
Smell the coffee! "Is That an Osler move??"
|
| mjl1717
Forum Hero
Topics: 959
Posts: 5,467
|
Alina in reference to your HI Yield q:
In females this enzyme blocks synthesis of androgens; thus masculinization of the ext. genitalia does not occur and ambiguous genitalia is not seen
Males because of this block are unable to produce androgen such as testosterone. Because adequate androgen is needed for male external genitalia, the ext. genitalia are only partialy masculinized or in severe case may have normal female genitalia {Endocrine Secrets by Michael T. McDermott. pg 195.} So only in the male might the genitals be underdeveloped
Seriously,I think becoming a female is more passive since testosterone, DHT, and MIF are not required.
Hope this helps.
___________________
Smell the coffee! "Is That an Osler move??"
|
| Alina T
Forum Elite
Topics: 17
Posts: 388
|
hey mjl, i wasnt refferring to 17 hydroxylase, but to
17 alpha Hydroxysteroid dehydrogenase (17 HSD) which converts androstenedione to testosterone.
i was comparing the 2 gene defects: 5 alpha reductase and 17 alpha HSD.
the clinical findings in these 2 are similar, meaning the external male genitalia are underdeveloped (low DHT), BUT the structures that develop under testosterone influence are normal too in both, although in the second gene defect testosterone is deficient also.
i found it a little weird...
___________________
There are 3 types of people: those who make things happen, those who watch things happen, and those who wonder what happened.
|
| mjl1717
Forum Hero
Topics: 959
Posts: 5,467
|
Sorry my mistake.
I guess we can do congenital adrenal deficiencies until infinity.
Ill probably stick with the top 4 or 5.
Thx
___________________
Smell the coffee! "Is That an Osler move??"
|
|
| |
| | | | | | | | | | | |
Similar forum topics