phuluong2k
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What is the difference ?
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| adeelmd
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bowen is white and bowenoid is reddish-brown... erythplasia of querat is bright red.... that's all i can remember... can anyone confirm??
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where i lay my head is home.
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| Kazem
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Bowen’s disease
Also called squamous cell carcinoma in situ
Age 35+; affects skin of shaft of penis and scrotum; also occurs in women
10% progress to invasive squamous cell carcinoma
1/3 may have unrelated visceral malignancy (lung, GI, urinary tract)
HPV positive
Gross: sharply demarcated, gray-white plaque with shallow ulcer and crusting
Micro: markedly dysplastic cells in all layers of epithelium, large hyperchromatic nuclei, multinucleated cells, dyskeratosis, vacuolization, acanthosis, hyperkeratosis, stroma with vascular proliferation and chronic inflammatory infiltrate; atypical mitoses but intact dermal epidermal junction
Bowenoid papulosis
Sexually active young men (mean age 30), usually on skin of shaft, glans or scrotum
Associated with HPV 16 or 18
Almost never becomes invasive
May spontaneously regress
Gross: multiple, small, pigmented papular lesions, may resemble condyloma acuminatum
Micro: histologically resembles Bowen’s disease, but may have mild/heavy melanin pigmentation within the lesion; often spiky or flat appearance, may have less cytologic atypia
taken from: http://pathologyoutlines.com/penscrotumpf.html#bo...
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| phuluong2k
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good answer
thank
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