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Author19 Posts
  #1

You are on a surgical rotation. Three days ago, you got to close the incision on the ‘big’ surgery that took ten hours. On attending rounds, you are asked the following question: ‘If we were to biopsy your perfectly closed and healing wound, what would we expect to find?’

A. Granulation tissue, a large amount of neovascularization, and evidence of epithelial proliferation

B. The incision filled with a clot

C. Macrophages and granulation tissue

D. Neutrophils, mitoses in the epithelial basal cells, and closure of the wound site

E. Proliferation of fibroblasts, enough collagen deposition to produce a small scar, and no inflammation or newly formed vessels


  #2

come on guys this is easy :icon_cyclop:


  #3

MY guess is -E


  #4

I've rearranged this process and the correct answer is D .

B. The incision filled with a clot (first 24h)

D. Neutrophils, mitoses in the epithelial basal cells, and closure of the wound site (within 24 to 48h)

C. Macrophages and granulation tissue

A. Granulation tissue, a large amount of neovascularization, and evidence of epithelial proliferation

E. Proliferation of fibroblasts, enough collagen deposition to produce a small scar, and no inflammation or newly formed vessels


  #5

my answer is C


  #6

I think it is A

Phase 1 - acute inflammation+ vasodilation+increased permeability>fluid accumulation -[ within 24 hrs] -recollect wounds are oozy in begining-epithelium starts growing with 2 hrs .

Phase 2- granulation+ neovascularization- 24-48 hrs + mono and lympho (T subsets)[ mono secrete growth factors]-

Phase 3 - Fibroblast proliferation/mild deposition - 48-72 hrs - very diagnostic-recollect from surgical ward round- fluid oozing decreases-dressings are not changed after 72 hrs

Phase 4- epithelization/ moderate collagen -after 72 hrs-collagen deposition is Maximum between 1-3 weeks


any corrections guys?

Deepak :wink:


  #7

ritu plz tell the answer


  #8

It would be choice C


  #9

I agreee with Maty-answer d


  #10

i think it is C
please ritu tell us the correct answer.


  #11

I think its C too.....but A is a close contender!


  #12

the correct answer is A. the third day granulation tissue start


  #13

5 years later digging it out....

going with C.


  #14

Nice dig up GG grin

Me too go with C.


  #15

Does granulation tissue appear in 3 days..??raised eyebrow

How is it C..?? Plz explain


  #16

me too go with c nod


  #17

VamAppu wrote:
Does granulation tissue appear in 3 days..??raised eyebrow

How is it C..?? Plz explain


yes granulation tissue appear from 3 to 7 days


  #18

i was between E and C... put E because i fixated on (your perfectly closed and healing wound),, so thought the wound healing here wouldnt nicssate inflammatory reaction.... apparently i am mistaken smiling face


  #19

cnodnodnodcool





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