drshabs
Forum Elite
Topics: 61
Posts: 205
|
can anyone plz explain why there is hyperlipidemia(increase s.cholestrol in nephrotis syndrome?
i know there is increase hepatic production but how n why?
plz someone help <:help:>
|
| RuMi
Forum Newbie
Topics: 4
Posts: 18
|
i believe, although im not entirely certain, that its a bystander affect. meaning, the liver trys to rev up the production of albumin and other proteins lost and at the same time the production of the lipids go up. sorry, thats all i know. :?
|
| mdwannabe
Forum Guru
Topics: 37
Posts: 1,133
|
I don't think there is a clear phys explanation to this phenomenon, part of it is due to loss od oncotic pressure, and attempt of body to replace some pull to vascular fluid.
___________________
"Life not lived for others, is not worth living" Uncle Einstein
"A life is not important, except in the impact it has on other lives" -Jackie Robinson
|
| drshabs
Forum Elite
Topics: 61
Posts: 205
|
thanks rumi n mdwannabe!!!
|
| step12005
Forum Senior
Topics: 27
Posts: 122
|
Hyperlipidemia is common in nepherotic syndrome but the underlying explaination is quite complicated. In some patient it is the result of increased VLDL, LDL and decreased HDL. While in some others, it's because of the decreased lipid usage. These come from the big 'robbin's pathology'. Hope that it helps.
|
| drshabs
Forum Elite
Topics: 61
Posts: 205
|
thanks step12005 that was good!
|
| Dr. Hussam
Forum Junior
Topics: 5
Posts: 56
|
the reason is that due to the protein loss, there's decreased production of lipoproteins which are used to carry lipids in the blood.
|
| Kazem
Forum Elite
Topics: 76
Posts: 296
|
Dr. Hussam are you sure there is decreased production of lipoproteins? because as far as I know it is vice versa. please elaborate. Thanx
|
| vermdocamit
Forum Newbie
Topics: 1
Posts: 23
|
Nephrotic syndrome----> Sugar loss----> Decreased energy resources-->
----> Glycolysis-----> Fat mobilisation-----> hyperlipidemia.
and
Protein loss----> Decreased oncotic pressure --- leads to --->
1. decreased VLDL clearance ( hypertriglyceridemia).
2. increased hepatic productionn of lipids ( apoprotein B lipoproteins).
___________________
<---- Jump first ----then think.----->
|
|
| |
| | | | | | | | | |
