sr
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at high altitudes, people get chronically hypoxemic because barometric pressure is decreased and as a result alveolar and arterial po2 are also decreased. in response, you hyperventilate, increase poduction of RBCs (by stimulation of remal production of erythropoietin), 2,3-DPG concentrations are increased (right shift in the hb-o2 sat curve, i.e., decreased hb affinity for o2), and pulmonary vasoconstriction takes place (which can lead to right ventricular hypertrophy).
-BRS physio.
is that what you were looking for?
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Los Angeles, CA, USA.
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so u mean there is a decrease in SaO2!!!!!!
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| sr
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sorry yes. at high alt, o2sat decreases and there is a physiologic response as explained above.
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Los Angeles, CA, USA.
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thx a lot ....i was looking for the same :lol: :lol:
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| merijung
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"sr" wrote:
at high altitudes, people get chronically hypoxemic because barometric pressure is decreased and as a result alveolar and arterial po2 are also decreased. in response, you hyperventilate, increase poduction of RBCs (by stimulation of remal production of erythropoietin), 2,3-DPG concentrations are increased (right shift in the hb-o2 sat curve, i.e., decreased hb affinity for o2), and pulmonary vasoconstriction takes place (which can lead to right ventricular hypertrophy).
-BRS physio.
is that what you were looking for?
Hi sr,
Your explanation is good.At high altitude,hypoxemia is because of decreased barometric pressure and hypoxemia means low SaO2 ( decreased O2 binding to Hb ) ..please correct me if I am confuse here?Is there always low SaO2 in hypoxemia caused by any reason (not only by high altitude?)
THANKS in advance !
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| sr
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basically there are 5 causes of hypoxemia: low inspired p02 (e.g., high altitude), hypoventilation (e.g., CNS dysfunction, anatomic, obstructive or restrictive lung disease), diffusion impairment, v/q mismatch, and (r-l) shunt.
hypoxemia means reduced oxygen in the blood, which i guess is the same as low SaO2. i looked all over the web and hypoxemia is a shady word, but i think it is safe to assume that hypoxemia means low SaO2.
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| merijung
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Thanks sr P
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| wxyz790
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A+
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| phuluong2k
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Hi SR
I have just had a look at Goljan note
He say that hypoxemia is reduction in amout of oxygen in dissolved in plasma, that means a low PaO2
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| kmp
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saturation (SaO2) is affinity of oxygen to hemoglobin. (oxygen binding to hemoglobin)
Hypoxemia --its the reduced oxygen in the bood.
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