usmlebuzz
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An 18-year-old male immigrant from West Africa presents with a maculopapular rash on his palms, soles, and lower extremities. He states that the rash started on his face, then spread over his body. A more detailed history reveals that rhinorrhea, cough, and photophobia were initial symptoms but have already resolved. Which of the following is a known complication of this infection?
A. Aplastic anemia
B. B-cell lymphoma
C. Loss of PPD skin test accuracy
D. Orchitis
E. Reye's syndrome
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| Yulia
Forum Elite
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It's measles. C.
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| usmlebuzz
Forum Elite
Topics: 93
Posts: 263
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yup [-o<
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| Malaysian
Forum Guru
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why is the answer C.....how does measles change PPD readings?I think its reye's syndrome.
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| mani
Forum Guru
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measles suppresses cell mediated immunity, can lead to false negetive PPD
reye's syndrome at 18 yrs of age???
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| Malaysian
Forum Guru
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Oh...thanks mani.....I was not aware that measles suppresed CMI....would you know the mechanism....any other infection I should be aware of which suppresses immunity(apart from HIV)???
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| mani
Forum Guru
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only one i can recall at the moment is measles. it impairs T cel function. Immunoglobulins are unimpaired
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