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Kaplan Qbank USMLE



Author3 Posts
  #1

blueprints step 1 q&a says:

carbon monoxide is bad for two reason. first, it binds to hb 200-250 times more than oxygen. second, it causes whatever oxygen is bound to hb stay bound to hb, creating a left shift in the oxygen-hb dissociation curve. that means the curve with the greatest percentage of carbon monoxide will bind oxygen with the greatest affitity.

is the second comment ture? i thought carbon monoxide would compete away the oxygen which was originally bound there away from hb. a

  #2

co will left shift the curve and increase the affinity for oxygen (remember how binding to spots on hb increases the affinity of binding other spots).. but the curve will flatten much quicker cuz the % saturation could never reach 100. (since the sites are taken up by CO)

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  #3

thanks a lot!







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