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Kaplan Qbank USMLE



Author16 Posts
  #1

After living at an altitude of 3500mts for 2 months,a subject will have
A)higher than normal PCO2
B)elevated hematocrit
C)abnormally low pressure in pulmonary artery
D)elevated erythropoeitin.

  #2

I think it's B

  #3

why not erythropoietin?

  #4

to me both b and d r correct

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  #5

I think erythropoietin will be up in the first few days but after a while when there is an increase in the number of red blood cells, the stimulus for erythropoietin production has deminished.

  #6

the given ans is hematocrit.first i was confused between B and D.but now i feel it as hematocrit because its more appropriate than erythropoetin as inc in erythropoeitin would result in inc in hematocrit due to polycythemia.

hope its correct.
thanks guys for ur explanation.

  #7

my point is that compensation is never complete and erythropoitin will be higher than normal. same is said by kaplan physio in the table regarding this topic

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  #8

B

  #9

i agree with mani the rythropoitin levels will also be higher than normal

yes raised hct is a correct option but erythropoitin is also corect can nay onme explain

  #10

may be the question wants to determine the time lag..

in earlier weeeks perhaps, EPO wud rise but HCt wudnt or sumething

but this is 2 months old..duz any one know if other compensatory changes like hi DPG enough to deal with the hypoxemia at a lower EPO??


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  #11

perhaps changes in plasma volume will also occur so the RBC mass ( or RBC /kg of the pt increases but HCT duznt.

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  #12

EPO is elevated due to hypoxia
2 mths later he can;t still have hypoxia

climitization will take place and EPO should be back to normal will elevated Hct


  #13

actually yes !! thanx!! HCT increase improves O2 CONTENT...so pO2 will be low, content normal due to the high hematocrit but EPO will be less elevated

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  #14

yes, full compensation would have occured for the hypoxemia in 2 months. so stimulus for erythropoeitin production would have reduced or be gone.

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  #15

B

  #16

b

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