adeelmd
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aldosterone doesn't go up in 17 hydroxylase def. cuz 11 deoxycortisol is increased due to increased acth, which is why you would get htn, and that would lead to a decrease in renin secretion, then aldosterone would decrease and you'd get htn with hyperkalemia???? doesn't that make sense????
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| mani
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rethink considering that deoxycorticosterone has mineralocorticoid antivity
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| adeelmd
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so aldo would not go up in 17 hydroxylase, but you would have htn with hypokalemia....
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| mani
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yes aldo will not be high, but not due to decreased synthesis rather due to feedback inhibition
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