rajeev
Forum Junior
Topics: 5
Posts: 62
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hey YU .. here a cupla QNs off ans .. the prob is that most of the 'togh ans QNS are represented graphically and i cant put em down here ..
these are qns which i jumped the gun and answered too gast andd got em wrong ...
1.in treating hypretension , Orthostatic hypotension occurs most with
a. clonidine
b. hydralazine
c. methyldopa
d.propranolol
2. a suitable drug in producung a brief increase in cardiac vagal tone ?
a.ergotamine
b. digoxin
c. edrophonium
d.PAM
e.Pyridostigmine
3.a patient is taking high doses hyradlazine for HT and a cupla months later blood work shows a moderately severe hemolytic anaemia ... drug induces SLE... if i the patient was dumb and i cant get a history ... what organ pathology would be lacking in 'this drug induced SLE patient ' compared to the non induced SLE... this patient would lack SLE would lack pathology in
a. kindey
b. musculoskeltal system
c. skin
d.cardivacular sysem
hmmmmm.... nice job these guys have huh composing USMLE QNS.... 
4.postual hypotension is a recog S effect exept in
a. venodialtors
b.ganglion blockers
c.alpha receptor bloclers
d.beta blockers
e. large doses of diuretics
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| Yulia
Forum Elite
Topics: 19
Posts: 240
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Hi, thank you very much, that was fast 
1. I have no clue. Neither of these should produce Postural hypotension. If I had to choose - Methyldopa. Don't ask why.
2. edrophonium. Surely has a brief action duration, not positive about suitability.
3. kidney
4. d.
This is frustrating...
Did I get everything wrong?
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| Yulia
Forum Elite
Topics: 19
Posts: 240
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Family has a child with Edwards sd, and they want to know the risks of producing second diseased child. DNA of both parents and baby is studied. There were RFLPs of 4 haplotypes associated with centromere of 18th chromosomes: W,Z,L,X (Boston's Classic Rock ). Father has genotype WZ , mother LX, baby is found to have ZLL. Can you tell exactly where (in which parent) and when (what stage of meyosis) nondisjunction occurred?
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| Yulia
Forum Elite
Topics: 19
Posts: 240
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Another one is on HIV testing
17 y.o. heroin abuser gives birth. Testing done on a baby right after and ELISA is positive and Western blot reveals 3 bands. From these results you can conclude that:
a. mother has been infected with HIV
B. baby has been exposed to HIV
C. baby has been infected with with HIV
D. mother has been exposed to HIV
E. mother and baby have been infected with HIV
F. can't diagnose
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| usmlebuzz
Forum Elite
Topics: 93
Posts: 263
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I think for the first one it is .....1st meiotic div as 2 L from mother came in baby
and for the second one both are hiv +ve as > 2 bands on western blot is considered +ve :roll:
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| rajeev
Forum Junior
Topics: 5
Posts: 62
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YU !!!
great going !!! the last three were bab g on target!!
abt qn i .. actually it was a QN to a Qn which had ... i wouda thought clonidine
hmmm.. now to the genetics..
forget abt qn i ..i never got the hang of meiosos .. what kinda classic rock station has a name like that ???
abt 2.. i would think that the baby has been exposed ..sigh !!!!
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| Yulia
Forum Elite
Topics: 19
Posts: 240
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Close on a second one, but they say you can't really tell who made these antibodies. You can tell for sure that mother has been infected, so her IgG crossed placenta and that's what we see in this baby. So, we don't know if baby even was exposed to the virus.
On a meyosis ? just see who the extra chromosome came from: the extra one is definitely L, so it came from mama. If nondisjunction occurred in meyosis 1 like ritu suggested, the baby would have genotype ZLX, cause there would be a chromosome nondisjunction. LL in mama's gamete actually suggests sister chromatid nondisjunction in meyosis 2.
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| rajeev
Forum Junior
Topics: 5
Posts: 62
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aye aye capatain !
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