mjl1717
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When you say a virus is positive stranded RNA -what EXACTLY does that mean?
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| Renegade
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Hi there, mjl1717. RNA + means, as far as I know, that such a particle is infectious as it is: it's all you need to start infection of a cell, since it's like mRNA.
Obviously RNA - virus required not only RNA but also other proteins for replication to begin...
Now, if a cientist (let's say he has access to all equipment available) is given an RNA particle, is it possible for him to tell if it's + or - just by studying the particle itself?
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| bhallaji
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These are viruses with a single-stranded RNA genome of "positive" polarity. This means that the genome also serves as mRNA; it can be directly translated. Positive strand RNA viruses replicate in the cytoplasm. Newly entered, uncoated viral RNA is immediately translated on host ribosomes to yield viral proteins needed for replication
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| Bio
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Exactly, and RNA(-) STRANDS ALSO REPLICAT IN THE CYTOPLASM, BUT THE MUST CARRY THEIR OWN RNA dependent-RNA POLYMERase; and because they must carry their only polymeras, to produce a RNA+ strand, they are not infectious nucleic acid.
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