Vai
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(Q book) A 35-year age old man present to ER with intense back pain. After several hour he passes a kidney stone. Laboratory analysis of stone reveals that is composed of struvite. Infection with which of following organism promotes the production of stone?
A E.coli
B Proteus Miriabilis
C Pseudomonas
D Staphylococcus Spr.
E Ureaplasma urealyticum
The correct answer is B without any objection, but what about answer E it seems to me a good option according Kaplan lectur note( produces urease,.., can cause renal calculi).
In Q explanation they say: choice E can produce urease(like Proteus), but is responsible for urethritis, not stone- in contradiction with lecture. Where is the mistake, in explanation or in lecture notes
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| bactitech
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I DO know that P. mirabilis is MUCH more common of a urinary tract pathogen than Ureaplasma. PRMI can live in the crypts of the stones. Urine infected with PRMI is alkaline. I don't remember the chemistry of the whole thing, but it probably has something to do with precipitation and stone formation.
Ureaplasma, BTW, doesn't grow on regular culture media. Special cultures must be taken and even at our big hospital, this is a send-out test. I'm not sure how these specimens are handled or what they are grown on.
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Clinical Microbiology since 1974
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