vallmo
Forum Junior
Topics: 25
Posts: 37
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If the GFR declined by 50% and the filtered load of K+ also declined by 50%, would the remaining kidney be able to maintain K+ balance? If so, how?. If not, would the subject become hypercalemic?
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| mani
Forum Guru
Topics: 104
Posts: 1,403
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i think plamsa K will ultimately remain unchanged. initially it will rise which will do 2 things
1. increased filtered load of K
2. stimulatiion of aldosteron secretion
these will return the k backl to normal
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| luckiest
Forum Senior
Topics: 12
Posts: 82
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My hypothesis is: Base on formula
Filtered load = GFR X [K+]
SO if u calculate from the questions
0.5(Filtered load )= 0.5(GFR) X [K+]
That will say that the k concentration remain the same.
So there will be noresponse in calcium or aldosterone.
LIke I say it's a hypothesis feel free to correct and explain more :roll:
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| drmamu
Forum Elite
Topics: 43
Posts: 188
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Hai,
Read first few pages Nephrology in Harrison. Potassium, bicarbonate, uric acid folows curve B in progression of renal failure. They will start rising only if the gfr falls to less than 25% of normal
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